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Dimitrios Topalis Selected Research

Antiviral Agents (Antivirals)

1/2021An MHV-68 Mutator Phenotype Mutant Virus, Confirmed by CRISPR/Cas9-Mediated Gene Editing of the Viral DNA Polymerase Gene, Shows Reduced Viral Fitness.
10/2020Viral fitness of MHV-68 viruses harboring drug resistance mutations in the protein kinase or thymidine kinase.
10/2020[Herpes simplex virus resistance to antivirals].
4/2018Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.

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Dimitrios Topalis Research Topics

Disease

3Neoplasms (Cancer)
12/2022 - 04/2018
3Infections
01/2021 - 10/2020
1Herpetic Keratitis
10/2020
1Virus Diseases (Viral Diseases)
10/2020
1Latent Infection
10/2020
1Merkel Cell Carcinoma
08/2019
1Inflammation (Inflammations)
04/2018

Drug/Important Bio-Agent (IBA)

4Antiviral Agents (Antivirals)IBA
01/2021 - 04/2018
2Cidofovir (Vistide)FDA Link
10/2020 - 04/2018
1trametinibIBA
12/2022
1sapanisertibIBA
12/2022
1Acyclovir (Aciclovir)FDA LinkGeneric
10/2020
1FoscarnetFDA LinkGeneric
10/2020
1Polyomavirus Transforming AntigensIBA
08/2019
1Neoplasm Antigens (Tumor Antigens)IBA
08/2019
1Oncogene Proteins (Oncogene Protein)IBA
08/2019
1NucleotidesIBA
04/2018